Circa 1310 BCE- First Red Heifer was prepared one day after the inauguration of the Tabernacle as Moses performed the first purification using this process. It was used to ritually purify the Jewish nation in preparation for the bringing of the Paschal Lamb in the newly erected Tabernacle.
1283- Jews of Mayence, Germany, were massacred.
1492- King Ferdinand and Queen Isabella of Spain signed a decree expelling all Jews who refused to convert to Christianity. Tomas de Torquemada served as "Grand Inquisitor," charged with uncovering those who continued to practice Judaism in secret (called Conversos or Marranos - "pigs"). In the ensuing Inquisition, an estimated 32,000 Jews were burned at the stake in elaborate public ceremonies, and another 200,000 were expelled from Spain. At the time, Jews held many prominent posts in Spain.